Thieme-Verlagsdatenbank-PrePrint is the advance database of the Thieme-Verlagsdatenbank. It carries highly topical documents even before their publication in print. If an article appears in the printed edition, it is included in the Thieme-Verlagsdatenbank and is deleted from the PrePrint database.
Apart from absence of the volume and year number, the fields of both databases coincide with one another. The documents from currently around 40 medical and scientific journals of the Thieme Verlag are linked to the corresponding fee-paying full texts. Bibliographic information and abstracts are included. Full texts are published on a fee-paying basis in the original language (English, German and French) as PDF files. Furthermore, they are linked to corresponding publication references from other bibliographical databases such as MEDLINE or EMBASE.
| Subject Coverage | Medicine and related fields |
|---|---|
| Type | Literature database |
| Language | English |
| Sources | Approx. 40 journals from Georg Thieme Verlag |
| Superbases | There are predefined databases groups (superbase) for several subjects. The database Thieme-Verlagsdatenbank-PrePrint is part of the following superbases: |
| File Size | 1,038 (Status 06/2011) |
|---|---|
| File Data |
You will find the number of database records in the current update status. |
| Update Cycle | Daily |
Journals of the Thieme-Verlagsdatenbank-PrePrint are labeld with e-print: List of Journals
Researching in the Thieme-PrePrint-Database is recommended only if full texts are required exclusively or documents from journals are searched for which are not indexed in other bibliographic databases. As a special highlight the full texts of Thieme journals are furthermore linked with relevant documents in other bibliographic databases like MEDLINE and EMBASE. Even if the Thieme-Verlagsdatenbank-PrePrint is not opened itself, the "book symbol" refers to an available full text. Thus, full texts are procurable online without laboriously ordering in a library. Requested online full texts are always liable to fees.
Standing orders (SDI) are possible for Premium customers.
The following document sections are considered with the free text search (FT):
Abstract (AB)
Document type (DT)
Title (TI)
Uncontrolled Terms (UT)
Search language(s) in the basic index:
English.
Explanation:
D = DISPLAY F = FIND S = SHOW
(F): field is searchable
only via basic index
| Command | Field Name | Examples | Notes |
|---|---|---|---|
| (F) S | AB Abstract | F mistletoe extract/AB | In approx. 90 % of the documents. |
| (F) | ABG Abstract German | F analyse?/ABG | Display with D F=AB |
| D F S | AI Abstract Indicator | F AI=abstract online | Search for citations with an abstract online. |
| D F S | AU Author | F AU=matthes h | End-masking required, if first name is not known. |
| S | AUL Author long | AUL: Matthes Harald | If known first names of authors written in full. |
| D F S | CS Corporate Source | F CS=charite berlin | |
| D F S | DT Dokument Type | F DT=editorial | editorial, letter and news available. |
| D DT=? | Lists the available document types. | ||
| D F S | DOI Digital Object Identifier | D DOI=? F DOI="10.1055/S-0028-1085571" |
Must be set in quotation marks. A DOI is a unique and persistent identification code for digital objects. |
| D F S | ISSN International Standard Serial Number | F ISSN=1439-9903 | Hyphen recommended. |
| D F S | EISSN Electronic International Standard Serial Number | F EISSN=1098-8785 EISSN: 1098-8785 /20081007/ |
Shown is also the electronic publication date in this field. See also field PDE. Also searchable in the field ISSN. |
| D F S | JT Journal Title | F JT=sleep breath D JT=sleep? |
Quotes required. Part of SO. |
| D F S | LA Language | F ... AND LA=germ | Language of the document. |
| D F S | ND Document Number | F ND=TVs-2002-32772 | Unique Number of Document. Publication Year of Volume integrated. |
| D F S | OTI Original title | F obstkernsaspiration/OTI | In German, French, English available. |
| D F S | PAGE Page | F PAGE=35-42 | Part of SO. |
| D F S | PD Publication Date | F PD=20091111 F PD=2009? |
Part of SO. |
| D F S | PDE Publication Date Electronic | F PDE=20080218 F PDE=2008? |
Publication Date of the electronic version of a journal. Shown as part of the field EISSN in the document. |
| D F | PPS PreProcessed Searches | D PPS=? | Shows all subjects for whose precasted search profiles are available (see appendix). |
| F ... AND PPS=human | Search for all documents relating (also) to humans. | ||
| D F S | PU Publisher | F PU= thieme PU: Georg Thieme Verlag Stuttgart, NewYork |
Here always Georg Thieme Verlag Stuttgart, New York. |
| D F S | PY Publication Year | F PY=2010 | Part of the Source-field (SO). |
| S | SO Source | SO: Suchttherapie; Vol. 3 (Suppl. 1) p. S78-S82; 200207 | Contains JT, VOL, ISS, PAGE, PD. |
| (F) S | TI Title | F alternative strateg?/TI | All titles in English, partly original titles in German and French available. |
| D F S | UT Uncontrolled Terms | F UT=infection F infection/UT D UT=infection |
Searchable as of 01/2006. Available in German and English. Not in each document available. |
By means of the commands SHOW (S) / MAIL / SDI.
Corresponding to the copyright rules use the parameter USE=DLOAD if necessary.
You may ask for all data fields, single data fields, or sets of data fields. If the output fields are not specified explicitly, the standard field set (F=STD) is used in all output commands.
Output field sets:
| Command | Field Set | Associated Datafields |
|---|---|---|
| F=STD | Standard | As ALL |
| F=ALL | all fields | ND, AU, TI, SO, DOI, PU, LA, ISSN, EISSN, CS, DT, UT, AB |
| F=BIB | bibliographic fields | ND, AU, TI, SO, DOI, PU, LA, ISSN, EISSN, CS, DT |
Database selection in ClassicSearch: SBAS TVPP
Subject: Therapy of hepatitis
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 963 | TVPP |
| S= | 2 | 65 | Cancer? |
| 3 | 179 | Therap? | |
| 4 | 25 | 2 and 3 |
2/1 of 1 DIMDI: Thieme-Verlagsdatenbank PrePrint (TVPP) © Thieme-Verlag - Document Price:0.00 €
| ND: | TVPPs-0028-1110020 |
| AU: | Zhou S; Yu T; Zhang J; Liu S; Huo Y; Zhang Y |
| TI: | Sonochemotherapy Inhibits the Adhesion, Migration
and Invasion of Human Ovarian Cancer Cells with Highly Metastatic
Potential Sonochemotherapie inhibiert die Adhäsion, Migration und Invasion humaner Ovarialkarzinomzellen mit hohem metastatischem Potenzial |
| SO: | Ultraschall in Med /20100427/ |
| DOI: | 10.1055/s-0028-1110020 |
| PU: | Georg Thieme Verlag Stuttgart, New York |
| LA: | English |
| ISSN: | 0172-4614 |
| EISSN: | 1438-8782 /20100427/ |
| CS: | Institute of Life Science, Chongqing Medical University, Chongqing, China |
| UT: | ovary; chemotherapy; ultrasound; treatment effects |
| AB: | PURPOSE: Preclinical trials have shown that
sonochemotherapy is effective for human ovarian cancers. Therefore,
the effects of sonochemotherapy on cell adhesion and motility were
investigated in this study, considering their roles in cancer
metastasis. MATERIALS AND METHODS: Cell lines, HO-8910 and its
highly metastatic potential subline HO-8910PM, were subjected to
cisplatin, paclitaxel and sonochemotherapy (anticancer drugs
followed by insonation). Cytotoxicity was determined, and then cell
adhesion, migration and invasion assays were performed. RESULTS:
Neither cisplatin (0.5 mug/ml) nor paclitaxel (6.0 mug/ml) alone
led to cell death. The addition of ultrasound did not potentiate an
anticancer drug, suggesting that there was a threshold dose for a
cytotoxic agent employed in sonochemotherapy. The survival rate was
decreased when combining cisplatin and paclitaxel followed by
insonation. 6.0 mug/ml of paclitaxel completely suppressed cell
adhesion and motility, thus the concentration was decreased to 1.2
mug/ml. Migration and invasion assays were only successfully
performed in HO-8910PM cells. Cisplatin and paclitaxel inhibited
adhesion, migration and invasion, resulting in lower rates, which
were additionally decreased by insonation. No cell traveled through
the membrane when cisplatin, paclitaxel and ultrasound were
combined. Quantitative evaluations indicated that ultrasound
enhanced anticancer agents via synergistic and/or additive effects.
CONCLUSION: Ultrasound synergized a combined regime and
sonochemotherapy was a measure to suppress cancer spread. ZIEL: Präklinische Studien haben gezeigt, dass die Sonochemotherapie effektiv in der Therapie humaner Ovarialkarzinome ist. In dieser Studie wurden daher die Effekte der Sonochemotherapie auf die Zelladhäsion und Motilität in Bezug auf deren Rolle bei der Metastasenbildung untersucht. MATERIAL UND METHODEN: Die Zelllinien HO-8910 und HO-8910PM, eine Sublinie mit hohem metastatischen Potenzial, wurden einer Therapie mit Cisplatin, Paclitaxel und Sonochemotherapie (d. h. Chemotherapie gefolgt von Insonation) zugeführt. Die Zytotoxizität wurde analysiert und Zelladhäsions-, Zellmigrations- und Zellinvasionsassays durchgeführt. ERGEBNISSE: Weder Cisplatin (0,5 mug/ml) noch Paclitaxel (6,0 mug/ml) allein führten zum Zelltod. Der additive Ultraschall potenzierte beide Chemotherapeutika nicht, sodass eine Schwelldosis für zytotoxische Agenzien in der Sonochemotherapie anzunehmen ist. Die Überlebensrate reduzierte sich bei Kombination von Cisplatin und Paclitaxel mit nachfolgender Beschallung. 6,0 mug/ml Paclitaxel supprimierte die Zelladhäsion und Motilität vollständig und wurde daher auf 1,2 mug/ml reduziert. Migrations- und Invasionsassays konnten nur in den HO-8910PM-Zelllinien erfolgreich durchgeführt werden. Cisplatin und Paclitaxel inhibierten Adhäsion, Migration und Invasion, was zu niedrigeren Überlebensraten führte, die durch Beschallung zusätzlich reduziert wurden. Bei Kombination von Cisplatin, Paclitaxel und Insonation war eine Membranpassage für die Zellen nicht mehr möglich. Quantitative Analysen legen einen synergistischen und/oder additiven Effekt von Ultraschall und Chemotherapeutika nahe. SCHLUSSFOLGERUNG: Wir konnten die synergistischen Effekte von Ultraschall und einem kombinierten Therapieregime darstellen. Sonochemotherapie ermöglichte eine Suppression der Tumorstreuung. |
full text
Output format: SHOW F=ALL
Rüdigerstraße 14
70469 Stuttgart
Germany
Phone: +49 711 8931-0
Fax: +49 711 8931-298
List of the PreProcessed Searches
For the following subjects preprocessed searches are available:
AIDS
ANIMAL
CANCER
HUMAN