TOXBIO
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Detailed Information: TOXBIO (TB69)
TOXBIO contains the toxicological relevant parts of the database BIOSIS Previews. It covers worldwide literature, especially from Northern America and Europe. Sources include approx. 5,500 international serials, conference proceedings, books, and patents from the USA (as of 1985). Bibliographic information, indexing terms, CAS numbers, and abstracts (approx. 50 %) are searchable.
Content navigation
- Database Content: Subject Coverage | Type | Language | Sources | Superbases
- Database Resources: File Size | File Data | Update Cycle
- Query: User Aids | Special Notes | Vocabulary | Searchable Data Fields | Data Fields, alphabetical | Output of Search Results | Sample Search(es) | Sample Record(s)
- Contact: Producer | Contact Person
- Appendix: Appendix
Database Content
| Subject Coverage | Biology, medicine, pharmacology, environmental medicine Biochemistry, biotechnology, botany, human medicine, agricultural sciences, microbiology, neurology, pharmacology, toxicology, veterinary medicine, environmental sciences, zoology. |
|---|---|
| Type | Literature database |
| Language | English |
| Sources |
|
| Superbases | There are predefined databases groups (superbase) for several subjects. The database TOXBIO is part of the following superbases: |
Database Resources
| File Size | 2,004,738 (Status 06/2012) |
|---|---|
| File Data |
Growth per year: approx. 36,000 documents You will find the number of database records in the current update status. |
| Update Cycle | Weekly |
Query
User Aids
- BIOSIS Search Guide (BIOSIS)
- BIOSIS Previews List of Journals (Thomson Reuters)
Special Notes
The field CT contains up to 13 special parts. These are 11 of the 12 main branches of the BIOSIS-Authority File, and the MeSH Headings and Gene Names:
MAJOR CONCEPTS: hierarchical
SUPER TAXA (&Biosystematic Codes): hierarchical
ORGANISMS: flat
TAXA NOTES: flat
PARTS, STRUCTURES, AND SYSTEMS (of Organisms): flat
METHODS AND EQUIPMENT: hierarchical
DISEASES: flat
MESH HEADING (in approx. 10 % of the documents): flat
CHEMICALS AND BIOCHEMICALS: flat
GENE NAME: flat
SEQUENCE DATA: flat
GEOPOLITICAL LOCATIONS: hierarchical
GEOLOGIC TIME: hierarchical
The 12th main branch, the concept codes, is searchable with the CT field and the SH field, e.g.
D CT DOWN concept codes
F CT = phytopathology?
F CT = 54502
In the (SHOW) display they are only visible in the SC field. In the (SHOW F= DES) display there are visible in the SH field.
These main branches of the BIOSIS-Authority File are searchable
like a descriptor, e.g.: FIND CT=SEQUENCE DATA (seeks for all
documents with the special part SEQUENCE DATA).
It is possible to limit the search to a special part of the
CT field,
e.g.: FIND CT=primates/ORG
It is possible to search for terms being not only together in
one part of the CT field but also closely connected,
e.g.: FIND CT=(primates AND fetus)/SAME CONT
Each main branch represents a list or lists of descriptors (Controlled Terms). In part they have a hierarchical structure, i.e. with DISPLAY CT DOWN … you are able to display sub-terms. Additional information is available for each of the approx. 1,300 Controlled Terms from these lists (see under "vocabulary").
Standing orders (SDI) are possible for Premium customers.
Vocabulary
Controlled Terms (CT) (Controlled descriptors from the
"BIOSIS-Authority File"
Language: English
For several CTs the following additional information is available:
| Code | Field Name |
|---|---|
| ARS | Subject Area |
| BC | Biosystematic Code |
| BT | Broader Term |
| CC | Classification Code (Term Identifier) |
| NT | Narrower Term |
| NU | Accession Number (BIOSIS) |
| RT | Related Term |
| SC | Section Code (= ConceptCode) |
| SCN | Scope Note |
| SH | Section Heading (= ConceptHeading) |
| UF | Use For |
Concept Codes (SC), Concept Headings (SH) (Controlled
descriptors for broad subject areas)
Language: English
Biosystematic Codes (BC), Biosystematic Headings (BS)
(Controlled descriptors for higher taxonomic categories of indexed
organisms)
Language: English
Uncontrolled Terms (UT) (Uncontrolled and semi-controlled
descriptors)
Language: English
Searchable Data Fields
The following document sections are considered with the free text search (FT):
Abstract (AB)
Biosystematic Heading (BS)
Book Title (BTI)
Controlled Terms (CT)
Document Type (DT)
Section Heading (SH)
Terminology (TE)
Title (TI)
Uncontrolled Terms (UT)
Search language(s) in the basic index: English. Original titles searchable as of 1996.
Data Fields, alphabetical
Explanation:
D = DISPLAY F = FIND S = SHOW
1 : front-end-masking recommended
2 : searchable word by word with field label
3 : searchable only selectively
(F): field is searchable
only via basic index
| Command | Field name | Examples | Special features |
|---|---|---|---|
| (F) S | AB Abstract | F effect ?,ozone./AB | Only for BA-citations since 07.76. |
| D F | AI Abstract Indicator | F ... AND AI=? F AI=abstract online D AI=? |
Searching for documents with an abstract online. |
| D F S | AU Author | F AU=percy ke | Up to 100 authors. Authors are linked to an address and country in the field CS with a character, e.g. (a). |
| D F | BC Biosystematic Code | F BC=25102 D BC=25102 |
See BS. Contains also BS. |
| D 1 F S | BS Biosystematic Heading | F BS=coniferopsida? F felidae/BS D BS=?rhabdovir? |
Searchable from 1970 to date. Truncation is recommended, because new BS' include the year of introduction. |
| BS: Coniferopsida* | Headings with * mean: This is a new taxonomic description. | ||
| (F) S | BTI Book Title | F drug research/BTI | Part of SO. |
| D F S | CA Corporate Author | F CA=german society | |
| D F | CC Classification Code | F CC=2.1.4.2.2.5.24 | See also CT. |
| D CC T 2.1.4.2.2.5.24 | Display of broader and narrower terms. | ||
| D CC=2.1.4.2.2.5.24;ALL | Requesting additional information. | ||
| F CC D 2.1.4.2.2.5.24 | Narrower terms are included. | ||
| D 2 F 2 S | CF Conference | F CF=congress of toxicology D CF=? |
Contains meeting title, date, location, and sponsor, if available (see also field SA). |
| D F S | COU Author Country | F COU=USA D COU=? |
Part of CS. Since 1975 available. |
| D F S | CP Patent Country | F CP=usa | Only U.S. patents, searchable as of 1985. |
| D F S | CR CAS Number | F CR=50-81-7 | Partially searchable since 1969. Also part of TE. |
| D 2 F 2 S | CS Corporate Source | F CS=pesticid? F CS=united kingdom ,? Pharm?. |
Added to BA articles since 01.78;added to BA/RRM articles since 01.80. Searchable word-by-word. Contains also COU, and the eMail address of the author, if available. See also field AU. |
| D F S | CT Controlled Term | F CT=clinical techniques D CT=a? |
Partially searchable as of 1969/1970. See also: Special Features. |
| F CT=(primates AND fetus)/SAME CONT | Seeks for descriptors being closely connected. | ||
| F CT D clinical techniques | Narrower terms are included. | ||
| D CT T clinical techniques | Display of broader and narrower terms. | ||
| D CT=clinical techniques;ALL | Requesting additional information. | ||
| D CT=clinical trial;CC | Requesting the corresponding Classification Code. | ||
| D CT=primates;BC | Requesting the corresponding Biosystematic Code. | ||
| D CT=toxicology?;SC | Requesting the corresponding Section Code (Concept Code). | ||
| F CT D (new taxon modifiers AND arachnida)/SAME CONT | Searching for new taxonomic descriptions. See also field BS. | ||
| D CT=toxicology?;SH | Requesting the corresponding Section Heading. | ||
| F | /QF=xx Qualifier | D QF=? | DISPLAY of all Authority File branches and other special parts of the field CT in alphabetical order. |
| F CT=primates/organism F CT=clinical trial/met |
Restriction to a special Authority File branche. | ||
| D F S | DOI Digital Object Identifier | D DOI=? F DOI="10.1002/AB.20230" |
Must be set in quotation marks. A DOI is a unique and persistent identification code for digital objects. |
| D F S | DT Document Type | F ... AND DT=article D DT=? |
Some document types are searchable approx. as of 1999. |
| D F S | EDR Editor | F EDR=ashworth d | Searchable approx. as of 1987. Editor of a book. |
| D F S | EISSN Electronic ISSN | F EISSN=1552-4965 | Electronic International Standard Serial Number, also searchable via F ISSN=... . |
| D F S | EZ Enzyme Code | F EZ=ec 1.1.1.27 | Part of TE. |
| D F S | ISBN ISBN | F ISBN=0-12-182214-1? | International Standard Book Number. Searchable approx. as of 1980. Masking is often re-commended. |
| S | ISS Issue Number | ISS: 12 | Part of SO. |
| D F S | ISSN ISSN | F ISSN=0931-041x | International Standard Serial Number. |
| D 1 F 1 S | JT Journal Title | F JT=pediatr nephrol D JT=?toxicol? |
Long version and short version of journal title are searchable. Part of SO. |
| D F S | LA Language | F … AND LA=germ | Added to BA-articles since 01.78;added to BA/RRM articles since 01.80. Usage of LA Code not before 1980! |
| D F S | MED Media Type | F MED=print? D MED=? |
Searchable approx. as of 1994. |
| D F S | ND Number of Document | F ND=tbtoxb200600031523 D ND=? |
|
| D F S | NP Number of Patent | F NP=us 5958463 | Only U.S. patents, searchable as of 1985. |
| S | OTI Original Title | TI: (Untersuchungen zur ...) | Searchable approx. as of 1996. Part of TI. |
| D 2 F 2 S | PAA Patent Assignee | F PAA=council ? industrial research | Only U.S. patents, searchable as of 1985. Contains the name of the person or organization to whom the rights to the patent have been assigned. |
| S | PAGE Pagination | Page: 2264-2270 | Part of SO. |
| D F S | PCL Patent Classification | F PCL=549-216 D PCL=? |
Only U.S. patents, searchable as of 1985. Contains class number and subclass number. The numbers are of variable length and may include numbers, alphabetic characters, and punctuation. |
| S | PD Publication Date | Part of SO. | |
| D F S | PDG Patent Date Granted | F PDG=?1999? D PDG=? |
Only U.S. patents, searchable as of 1985. Contains the date found on the front cover of the "Official Gazette of the United States Patent and Trademark Office Patents" from which the patent record was taken (=patent issue date). Masking is recommended. |
| D F | PPS PreProcessed Searches | D PPS=? | Shows all subjects for whose precasted search profiles are available (see appendix). |
| F… AND PPS=human | Search for all documents relating (also) to humans. | ||
| D 2 F 2 S | PU Publishing Data | F PU=springer F PU=berlin |
Searchable approx. as of 1992. Contains publisher with an address. |
| D F S | PY Publication Year | F ... AND PY >= 1998 D PY=? |
Part of SO. |
| D F S | SA Supporting Agency | F SA=chinese society of toxicology | Contains the Meeting Sponsor approx. as of 1996. Part of CF too. |
| D F | SC Section Code | F SC=22508 D SC=22501 F CT=22508 |
Corresponds to Concept Codes, numeric. Also searchable with the field CT. In the (SHOW) display they are visible together with the headings. |
| D 2 F 2 S | SE Series Title | F SE=environmental, ? toxicology | |
| D 1 F 1 S | SH Section Heading | F SH= toxicology? D SH=?genetics? F SH=?genetics? F pesticides?/SH F CT=pesticides? |
Corresponds to the Concept Codes, alphabetic. Searchable from 1970 to date. Also searchable with the field CT. The Headings are often very long, masking is recommended. |
| S | SO Source | SO: Drug and Chemical Toxicology an International Journal for
Rapid Communication; Vol: 29 (1); p. 135 /2006/ |
Contains also JT, BTI, VOL, ISS, PAGE, PD, PY and URL. Direct link to full text of internet only journals. So far only very few documents. |
| D F S | TE Terminology | F TE=vitamin c F nitric oxide/TE F TE=50-81-7 F TE=ec 1.1.1.27 |
Contains also CR and EZ. |
| (F) S | TI Title | F diabetic retinopathy/TI | Contains the original title approx. as of 1997. |
| D F S | UT Uncontrolled Terms | F UT=personality F investigation/UT D UT=production? |
Searchable as of 1970. Not in each document available. |
| S | VOL Volume | VOL: 105 | Part of SO. |
Output of Search Results
By means of the commands: SHOW (S) / MAIL / SDI.
Corresponding to the copyright rules use the parameter USE=DLOAD if necessary.
You may ask for all data fields, single data fields, or sets of data fields. If the output fields are not specified explicitly, the standard field set (F=STD) is used in all output commands.
Output field sets:
| Command | Field Set | Associated Datafields |
|---|---|---|
| F=STD | standard | same as F=ALL |
| F=F2 | same as F=ALL, without EISSN | |
| F=ALL | all fields | ND, AU, CA, TI, CF, EDR, SO (incl. BTI, JT, PY, VOL, ISS, PAGE, PD, URL), PU, SE, LA, ISSN, EISSN, ISBN, CS, COU, DT, MED, SA, SH, CT, UT, TE (incl. CR, EZ), CR, PCL, PDG, PAA, CP, NP, BS, AB |
| F=BIB | bibliographic fields | ND, AU, CA, TI, CF, EDR, SO, PU, SE, LA, ISSN, EISSN, ISBN, CS, COU, DT, MED, SA |
| F=DES | descriptors | SH, CT, UT, TE, CR, BS |
| F=PAT | patents | PCL, PDG, PAA, CP, NP |
Sample Search(es)
Subject: Pesticides and Parkinson's disease in humans - is there a link?
This subject covers three concepts: a) pesticides, b) Parkinson's disease, c) human.
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1660549 | TB69 |
| S= | 2 | 45796 | PESTICID?/(TI;CT) |
| 3 | 29783 | CT=PESTICIDES | |
| 4 | 18182 | CT=PESTICIDE | |
| 5 | 131239 | SH="PEST CONTROL: GENERAL, PESTICIDES AND HERBICIDES" | |
| 6 | 5861 | SH="PUBLIC HEALTH - DISINFECTION, VECTOR CONTROL AND PESTICIDES" | |
| 7 | 136926 | 3 OR 4 OR 5 OR 6 | |
| 8 | 5517 | PARKINSON?/(TI;CT) | |
| 9 | 2607 | CT=PARKINSON DISEASE | |
| 10 | 2641 | CT=PARKINSON'S DISEASE | |
| 11 | 3069 | 9 OR 10 | |
| 12 | 181 | 7 AND 11 | |
| 13 | 83 | 12 AND PPS=HUMAN |
Sample Record(s)
2/1 of 1 DIMDI: TOXBIO (TB69) © Thomson Reuters
| ND: | TBTOXB200600031523 |
| AU: | Van Maele-Fabry G; Libotte V; Willems J; Lison D |
| TI: | Review and meta-analysis of risk estimates for prostate cancer in pesticide manufacturing workers |
| SO: | Cancer Causes & Control; VOL: 17 (4); p. 353-373 /MAY 2006/ |
| LA: | English |
| ISSN: | 0957-5243 |
| CS: | Van Maele-Fabry, Genevieve,Catholic Univ Louvain, Unite Toxicol
Ind and Med Travail, Ecole Sante Publ, Brussels, Belgium, genevieve.vanmaele@toxi.ucl.ac.be |
| COU: | Belgium |
| DT: | Article; Literature Review |
| SC: | CONCEPT CODES; 04500 ... Mathematical biology and statistical methods; 15506 ... Urinary system - Pathology; 16506 ... Reproductive system - Pathology; 22501 ... Toxicology - General and methods; 24004 ... Neoplasms - Pathology, clinical aspects and systemic effects; 37054 ... Public health: epidemiology - Organic diseases and neoplasms; 37056 ... Public health: epidemiology - Miscellaneous; 54600 ... Pest control: general, pesticides and herbicides |
| CT: | MAJOR CONCEPTS; Toxicology; Epidemiology (Population Studies);
Oncology (Human Medicine, Medical Sciences); Urology (Human
Medicine, Medical Sciences); Mathematical Biology (Computational
Biology); Pesticides; SUPER TAXA; Hominidae: Primates, Mammalia, Vertebrata, Chordata, Animalia; ORGANISMS; human (common) (Hominidae); TAXA NOTES; Animals; Chordates; Humans; Mammals; Primates; Vertebrates; METHODS AND EQUIPMENT; meta-analysis: mathematical and computer techniques; DISEASES; prostate cancer: urologic disease, reproductive system disease/male, neoplastic disease, epidemiology; MESH HEADING; Prostatic Neoplasms (MeSH); CHEMICALS AND BIOCHEMICALS; phenoxy herbicides: toxin, herbicide, pesticide; dioxin: toxin, contamination; furan: toxin, contamination |
| UT: | disease risk |
| TE: | dioxin/1746-01-6; furan/110-00-9 |
| CR: | 1746-01-6; 110-00-9 |
| BC: | 86215 ... Hominidae |
| AB: | Purpose The purpose of the present paper is to review cohort studies that examined the occurrence of prostate cancer in pesticide manufacturing workers in order to undertake a qualitative and quantitative evaluation of the risk as well as to assess the level of epidemiological evidence for each class of chemical compounds.Methods Following a systematic literature search, relative risk (RR) estimates for prostate cancer were extracted from 18 studies published between 1984 and 2004. All studies were summarised and evaluated for homogeneity and publication bias. As no significant heterogeneity was detected, combined RR estimators were calculated using a fixed effect model. Meta-analyses were performed both on the whole set of data and for each chemical class separately.Results The meta-rate ratio estimate for all studies was 1.28 [95% confidence interval (CI) 1.05-1.58]. After stratification by specific chemical class, consistent increases in the risk of prostate cancer were found in all groups but statistical significance was found only for accidental or non-accidental exposure to phenoxy herbicides contaminated with dioxins and furans. There was no obvious indication of publication bias.Conclusion The overall meta-analysis provides additional quantitative evidence consistent with prior reviews focusing on other groups exposed to pesticides (farmers, pesticide applicators). The results again point to occupational exposure to pesticides as a possible risk factor for prostate cancer but the question of causality remains unanswered. Epidemiological evidence did not allow identifying a specific pesticide or chemical class that would be responsible for the increased risk but the strongest evidence comes from workers exposed to phenoxy herbicides possibly in relation with dioxin and/or furan contamination. |
 full
text |
|
| *** End of SHOW *** | |
Output format: SHOW F=ALL
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Appendix
Appendix
List of the PreProcessed Searches (PPS)
For the following subjects preprocessed searches are available:
AIDS
ANIMAL
CANCER
HUMAN
MEETINGS
- Copyright: DIMDI -