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Detailed Information: Derwent Drug File (DD90, DD83)
Derwent Drug File (DDF) contains information on drugs and pharmaceutical sciences from over 40 countries. Sources include journals and conference proceedings. Bibliographic data, indexing terms, and abstracts are searchable.
Content navigation
- Database Content: Subject Coverage | Type | Language | Sources | Superbases
- Database Resources: File Size | File Data | Update Cycle
- Query: Special Notes | Vocabulary | Searchable Data Fields | Data Fields, alphabetical | Output of Search Results | Sample Search(es) | Sample Record(s)
- Contact: Producer | Contact Person
- Appendix: Appendix
Database Content
| Subject Coverage | Drugs, Pharmaceutical Sciences Pharmaceutical technology, pharmacology, pharmacokinetics, metabolism, therapeutic use, adverse effects, synthesis, analysis, biochemistry, structure-activity relationships, drug comparisons,and toxicology of drugs. |
|---|---|
| Type | Literature database |
| Language | English |
| Sources | Journals: approx. 1,200 |
| Superbases | There are predefined databases groups (superbase) for several subjects. The database Derwent Drug File is part of the following superbases: |
Database Resources
| File Size | 1,426,736 (Status 06/2012) |
|---|---|
| File Data |
Open Access file DD83: 1983 - to date
Subscriber file DW83: 1983 - to date You will find the number of database records in the current update status. |
| Update Cycle | Weekly |
Query
Special Notes
ABEX Extension Abstract:
The Extension Abstract is only accessible to Derwent Subscribers in database versions DW and contains a more extensive description of contents.
CT (Controlled Terms):
The field CT is divided into groups according to the relation of the descriptors to single drugs. Each important drug reported in the original paper is assigned a separate indexing "sentence" which links together all concepts related to that compound.
- Descriptors which are applicable to all drugs (common terms) can be found above the drug specific groups. As descriptors are conceptually linked it is possible to retrieve very specific search results by using the qualification "/same cont".
- The descriptors in the Controlled Terms field may be qualified by special aspects (roles). Their two letter abbreviations are attached to the CT by using a slash, e.g. CT=paracetamol/QF= ae(ae= adverse effect).
- Descriptors hyphenated in the printed Derwent thesaurus may be searched with or without the hyphen.
- Fullstops in thesaurus descriptors are removed, e.g. TOX. or LAB.ANIMAL appear as CT=TOX and CT=LAB ANIMAL.
- Quite often designations are divided into several controlled terms, e.g. High Density Lipoprotein appears as CT=HIGH and CT=DENSITY and CT=LIPOPROTEIN. Please search with F high density lipoprotein/CT or F CT=(high and density and lipoprotein)/same cont
- In addition to specific controlled terms higher terms are present in the record, e.g. in the case of CT = VALERIANA: CT = BOTANY is available.
Standing orders (SDI) are possible for Premium customers.
Vocabulary
Controlled Terms (CT)
Section Codes (SC), Section Headings (SH)
Index Codes (IC), Index Terms (IT)
CAS Number (CR) (available in the ongoing files)
Searchable Data Fields
The following document sections are considered with the free text search (FT):
Abstract (AB)
Controlled Term (CT)
Extension Abstract (ABEX) in Vers. DW
Index Term (IT)
Section Heading (SH)
Title (TI)
Search language(s) in the basic index:
English
Data Fields, alphabetical
Explanation:
D = DISPLAY F =
FIND S = SHOW
1 : front-end-masking recommended
2 : searchable word by word with field label
3 : searchable only selectively
(F): field is searchable
only via basic index
| Command | Field Name | Examples | Notes |
|---|---|---|---|
| (F) S | AB Abstract | F placebo/AB | English abstract, max. 100 words. |
| (F) S | ABEX Extension Abstract | F glaucoma/ABEX | Additional abstract with more details; only accessible to Derwent Subscribers (DW83, DW90). |
| D F | AI Abstract Indicator | F AI=? D AI=? F AI= abstract online |
Search for citations with online abstracts. |
| S | ASI Additional Source Information | ASI: 3 Fig. 2 Tab. 24 Ref. | |
| D F S | AU Author | F AU=bito 1z D AU= bito |
Max. 20 authors, prior to mid-1994. Max. 6 authors; max two initials for first name. |
| D 2 F 2 S | CNA Corporate Names | F CNA=univ? columbia D CNA= columbia |
|
| D F S | CO Coden | F CO=aropaw | International Journal Code; |
| D 2 F 2 S | COU Country, City | F COU=ger D COU= us? |
|
| D F S | CR CAS Number | F CR=130209-82-4 D CR= 1302? |
|
| D 2 F 2 S | CS Corporate Source | F CS=department ? ophth? D CS= ophthalmol? |
|
| D F S | CT Controlled Term | F CT=eye-disease F CT= eyedisease |
Hyphenated thesaurus terms may be used with or without hyphen. |
| D F | /QF = xx Qualifier | FCT=eye-disease/QF=TR FCT=eye-disease/(QF=TR;AE) F QF=dm |
Qualification by aspects (roles) (see appendix). |
| F(CT=glaucoma/QF=TR and CT=latanoprost/QF=TR)/same cont |
Linking to drug related context. | ||
| F high density lipoprot?/CT F ((diclofenac and cases)/CT) /same cont |
|||
| D CT=eye-disease | |||
| D F S | IC Index Code | F IC=t D IC= ? |
Codes for thematic groups (broad subject fields; see appendix). |
| D F S | ISSN Internat. Standard Serial Number | F ISSN=0003-9950 | |
| D F S | IT Index Term | F IT=therapeutics F therapeutics/IT D IT= ? |
Text version for thematic groups (see appendix). |
| D F S | JT Journal Title | F JT=arch ophthalmol? D JT= ?ophthalmol? |
|
| D F S | LA Language | F ... AND LA=germ D LA=? |
|
| D F S | ND Number of Document | F ND=DD1995-00020 | |
| D F | PPS PreProcessed Searches | D PPS=? | Shows all subjects for whose precasted search profiles are available (see appendix). |
| F ... AND PPS=human | Searches all documents relating (also) to humans. | ||
| D F S | PY Publication Year | F PY=1996 | |
| D F | SC Section Code | F SC=64 D SC=? |
Codes for drug related topics (see appendix) |
| D F S | SH Section Heading | F SH=clinical trials F clinical trials/SH D SH=? |
Text version for drug related topics (see appendix) |
| S | SO Source | SO: Arch Ophthalmol ; 114; No. 3; 268-73 1996 | Source is not searchable as SO; however parts of the SO such as JT, PY (see appropriate fields) can be searched. |
| (F) S | TI Title | F intraocular pressure/TI | English original title or English translation of non-English titles with indication of the original language. |
Output of Search Results
By means of the commands: SHOW (S) / MAIL / SDI.
Corresponding to the copyright rules use the parameter USE=DLOAD if necessary.
You may ask for all data fields, single data fields, or sets of data fields. If the output fields are not specified explicitly, the standard field set (F=STD) is used in all output commands
Output field sets:
| Command | Field Set | Associated Datafields |
|---|---|---|
| F=STD | Standard - with Extension Abstract (DW83, DW90 only) | same as F= ALL |
| F=ALL | All Datafields | ND, AU, CNA, TI, SO, ASI, LA, ISSN, CO, CS, COU, SC, SH, IC, IT, CT, CR, AB, ABEX |
| F=BIB | Bibliographic fields | ND, AU, TI, SO, ASI, ISSN, CO, LA, CNA, COU, CS |
| F=DES | Trial-Descriptors | SC, SH, IC, IT, CT, CR |
Sample Search(es)
Selecting base in DIMDI ClassicSearch: SBAS DD83; SBAS DW83; SBAS DD90; SBAS DW90;SBAS DERWENT DRUG
The structure of the field CT (Controlled Terms) is described in the Special Features section. Using controlled terms, especially in combination with qualifiers, very specific searches can be carried out in the ongoing files (List of qualifiers in the appendix).
Subject: Adverse effects of aciclovir
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1363333 | DD83 |
| S= | 2 | 601 | CT=ACICLOVIR/AE |
Using the qualification "/same cont" search results can be obtained, in which the searched controlled terms occur not only together in the CT-field but are also contextually linked to each other.
Subject: Heparin treatment of embolism
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1363333 | DD83 |
| S= | 2 | 756 | CT=(HEPARIN/QF=TR AND EMBOLISM/QF=TR) |
| 3 | 715 | 2/SAME CONT |
Profile table (alternative):
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1363333 | DD83 |
| S= | 2 | 715 | (CT=HEPARIN/QF=TR AND CT=EMBOLISM/QF=TR)/SAME CONT |
Searches can be performed using controlled terms which are mapped as higher terms to specific controlled terms.
Subject: Treatment of eye diseases with antibiotics
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1363333 | DD83 |
| S= | 2 | 949 | CT=EYE DISEASE/QF=TR AND CT=ANTIBIOTICS |
| 3 | 873 | 2/SAME CONT |
The codes or descriptors of the fields SC/SH and IC/ IT> enable searches for broad subject areas. (Lists of codes and descriptors in appendix). For this purpose qualifiers may be used without linkage to a CT.
Subject: Adverse effects of phytotherapy (publications since 1995)
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 1363333 | DD83 |
| S= | 2 | 267227 | (IT="ADVERSE (SIDE) EFFECTS") |
| 3 | 220346 | SH=ADVERSE REACTIONS | |
| 4 | 268869 | QF=AE | |
| 5 | 279235 | 2 TO 4 | |
| 6 | 10001 | CT=PLANT-SUBSTANCE | |
| 7 | 14257 | CT=BOTANY | |
| 8 | 2104 | 5 AND (6;7) | |
| 9 | 1100 | 8 AND PY>1994 |
Sample Record(s)
2/1 of 601 DIMDI: Derwent Drug File (DD90) © Thomson Reuters
| ND: | DD2010-45263 |
| AU: | Phiri S; Hoffman IF; Weiss HA; Martinson F; Nyirenda N; Kamwendo D; Fiscus SA; Chen CY; Miller WC; et-al |
| TI: | Impact of aciclovir on ulcer healing, lesional, genital and plasma HIV-1 RNA among patients with genital ulcer disease in Malawi. |
| SO: | Sex Transm Infect; VOL: 86 (No. 5); p. 345-52 /2010/ 3 Fig. 4 Tab. 49 Ref. |
| ISSN: | 1368-4973 CO:8584A |
| LA: | English |
| CNA: | Lighthouse-Cent.Malawi; Univ.London-Sch.Hyg.+Trop.Med.; Univ.North-Carolina; U.S.Cent.Dis.Contr.Prev.Atlanta; Min.Health-Lilongwe |
| COU: | Lilongwe, Malawi |
| CS: | Kamuzu Cent Hosp, Lighthouse Ctr, POB 106, Lilongwe, Malawi. (Phiri S, 13 Authors, e-mail: samphiri@lighthouse.org.mw). |
| SC: | 35 ... Adverse Reactions; 41 ... Virucides; 53 ... Infection; 64 ... Clinical Trials |
| IC: | T ... Therapeutics; M ... Microbiology; S ... Adverse (Side) Effects |
| LINKS: | 01 |
| LINK: | 01 |
| CT: | ACICLOVIR/TR; ACICLOVIR/AE; ACICLOVIR/RN; CARLSBAD-LABORATORIES/FT; GENITAL/TR; ULCER/TR; INFECTION,VIRUS/TR; HERPES-SIMPLEX/TR; AIDS/TR; NAUSEA/AE; EMESIS/AE; DIARRHEA/AE; CONSTIPATION/AE; HEADACHE/AE; GASTRALGIA/AE; RENAL-COLIC/AE; ASTHENIA/AE; PYREXIA/AE; ACQUIRED/TR; IMMUNODEFICIENCY-DISEASE/TR; GASTROENTEROPATHY/AE; NEPHROPATHY/AE; VIRUCIDES/FT; P O/FT; CASES/FT; IN-VIVO/FT; RANDOM/FT; DOUBLE/FT; CLIN TRIAL/FT; BLIND-TEST/FT; PLACEBO/FT; BLOOD-PLASMA/FT; ANTIVIRAL/FT; HIV-1-VIRUS/FT; HERPES-SIMPLEX-VIRUS-2/FT; CERVIX/FT; SEMEN/FT; CD4+-CELL/FT; LEUKOVIRUS/FT; VIRUS/FT; HIV-VIRUS/FT; HERPES-SIMPLEX-VIRUS/FT; HERPESVIRUS/FT; UTERUS/FT; THYMOCYTE/FT; LYMPHOCYTE/FT; TR/FT; AE/FT |
| AB: | This randomized, double-blind, placebo-controlled trial evaluated the impact of acyclovir on ulcer healing, lesional, genital and plasma HIV-1 RNA among 422 patients with genital ulcer disease in Malawi. 85% Of ulcers were healed at day 14 with no difference between treatment arms. Among 244 HIV-1/HSV-2 co-infected individuals, acyclovir reduced lesional HIV-1 RNA and seminal HIV-1 RNA, but not cervical HIV-1 RNA or plasma HIV-1 RNA. Episodic HSV treatment with acyclovir added to syndromic management does not produce a significant clinical benefit in this African population. |
 full text |
|
| *** End of SHOW *** | |
Output format: SHOW F=ALL
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Appendix
Appendix
1. List of the PreProcessed Searches (PPS)
For the following subjects preprocessed searches are available:
AIDS
ANIMAL
CANCER
HUMAN
2. List of Section Headings (SH) and Section Codes (SC)
* indicates not used after end 1986
| Section Codes | Section Headings | |
|---|---|---|
| * | 1 | Agriculture |
| * | 2 | Alkaloids |
| 3 | Antiallergics | |
| * | 4 | Analgesics |
| * | 5 | Analysis |
| 6 | Antibiotics | |
| * | 7 | Bioassay |
| 8 | Pharmacokinetics | |
| * | 9 | Cardiovascular |
| * | 10 | Chemotherapeutics |
| * | 11 | Corticosteroids |
| 12 | Antidiabetics | |
| * | 13 | Endocrinology |
| 14 | Enzyme Inhibitors | |
| 15 | Drugs in Fertility | |
| 16 | Gastrointestinal | |
| * | 17 | Physico-Chemical Techniques |
| 18 | Hematological | |
| * | 19 | Heterocyclics |
| 20 | Immunological | |
| * | 21 | Infection |
| 22 | Endogenous Compounds | |
| 23 | Antimicrobials | |
| 24 | Bones & Joints | |
| * | 25 | Neoplasia |
| * | 26 | Neurology |
| 27 | Molecular Biology | |
| * | 28 | Organochemical |
| 29 | Pharmaceutics | |
| * | 30 | Natural Products |
| * | 31 | Proteins & Lipids |
| 32 | Psychotropic | |
| 33 | Respiratory | |
| 34 | Toxicology | |
| 35 | Adverse Reactions | |
| 36 | Dermatological | |
| * | 37 | Steroids |
| 38 | Structure-Activity | |
| 39 | Kidney | |
| * | 40 | Veterinary |
| 41 | Virucides | |
| 42 | Vitamins | |
| 43 | Analgesics, NSAIDs | |
| 44 | Narcotics | |
| 45 | Anesthetics | |
| 46 | Corticosteroids | |
| 47 | Sex Hormones | |
| 48 | Prostaglandins | |
| 49 | Peptide Hormones | |
| 50 | Biological Response Modifiers | |
| 51 | Chemotherapy - clinical | |
| 52 | Chemotherapy - non-clinical | |
| 53 | Infection | |
| 54 | Antiseptics | |
| 55 | Fungicides | |
| 56 | Cardiants | |
| 57 | Antiarrhythmics | |
| 58 | Vasoactive | |
| 59 | CNS & Motor | |
| 60 | Autonomic | |
| 61 | ORL | |
| 62 | Ophthalmological | |
| 63 | Receptors | |
| 64 | Clinical Trials | |
| 65 | Drug Delivery | |
| 66 | Drug Interactions | |
| 67 | Children & Elderly | |
| 68 | Mutagenic | |
| 69 | Reviews | |
| 70 | Analysis | |
| 71 | Medicinal Chemistry | |
| 72 | New Drugs | |
| 73 | Trial Preparations |
3. List of Qualifiers (Roles)
| Codes | Names |
|---|---|
| AE | Adverse Effects |
| DI | Drug Interaction |
| DM | Metabolism |
| FT | Further Terms |
| OC | Other context |
| PH | Pharmacology |
| RC | Reference Compound |
| RN | Registry Name |
| TR | Treatment |
4. List of Index Terms (IT) and Index Codes (IC) (Thematic Groups)
| Index Codes | Index Terms |
|---|---|
| A | Analysis |
| B | Biochemistry |
| C | Chemistry |
| E | Endocrinology |
| G | Galenics |
| H | Herbicides |
| L | Legislation |
| M | Microbiology |
| N | Nutrition |
| P | Pharmacology |
| S | Adverse (Side) Effects |
| T | Therapeutics |
| V | Vitamins |
| W | Veterinary Medicine |
| X | Mathematics |
| Z | Zoology |
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