Database of Abstracts of Reviews of Effects


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Database of Abstracts of Reviews of Effects (CDAR94)
Other Reviews

The Database of Abstracts of Reviews of Effects (DARE; Other Reviews) contains structured summaries from systematic reviews which are published worldwide and which have passed a quality filter of the NHS-Centre for Reviews and Dissemination of the University of York, England. Abstracts of qualitatively highly-assessed reviews are found in the database. The bibliographical indications as well as the assessment criteria of the further works are listed. Bibliographical indications, descriptors as well as abstracts can be searched.

 

 

Database Content

Subject Coverage

Medicine and Related Fields

TypeLiterature database
LanguageEnglish
Sources

Cochrane Library: Reviews from medical databases and professional journals.

Superbases

There are predefined databases groups (superbase) for several subjects.

The database Database of Abstracts of Reviews of Effects is part of the following superbases:
XHTA, XMEDALL.

Database Resources

File Size17,084 (Status 06/2012)
File Data

You will find the number of database records in the current update status.

Update Cyclequarterly

Query

Special Notes

With every update the whole file is reloaded. Therefore standing orders (SDI) are not possible.

Vocabulary

Controlled Terms (CT): MeSH thesaurus with polyhierarchical structure
Language of vocabulary: English 

The hierarchical structure of the thesaurus allows a one step search for indented descriptors using the command FIND CT DOWN … (explosion). CT can be limited using more than 80 qualifiers, e.g. epidemiology of a disease (FIND CT=.../QF=ep). List of qualifiers see appendix.

Descriptors, describing the major topics of an article are weighted and marked in the document by an asterisk (HIV SEROPOSITIVITY/*). You can search for weighted descriptors with the command FIND CT=.../W=1.

The command DISPLAY CT TREE ... displays the structure of the thesaurus.

DISPLAY CT= ...  ;ALL displays all available additional information to a descriptor (see table below).

The following additional information for controlled terms (CT) is available:

Code Field Name Description
ANN Annotations Indexing annotations
AQ Allowed Qualifier Qualifiers allowed for limiting the controlled terms
CC Classification Code One descriptor may have several classification codes corresponding to the different branches in the polyhierarchic thesaurus
CR CAS- Registry- Number  
DA Date Date, the record was added to the system
ECOM Entry Combination Information on use of combinations for related concepts
HIS History-Notes Information on entry date of the descriptor and formerly used controlled terms
MAE Major Established Introduction date as major descriptor
N1 Preferred Name Preferred name of chemicals/td>
PACT Pharmacological Action Pharmacological action descriptor
PI Previous Indexing Previous Indexing
PMN Public MeSH Note Information on entry date of the descriptor and formaerly used controlled terms
SCN Scope Notes definitions
SYN Synonym Information on entry terms
USE Use Print Version

 

Searchable Data Fields

The following document sections are considered with the free text search (FT):

Abstract (AB)
Controlled Terms (CT)
Document Type (DT)
Title (TI)

Search language(s) in the Basic Index: Englisch

Data Fields, alphabetical

Explanation:

D = DISPLAY F = FIND S = SHOW
1 : front-end-masking recommended
2 : searchable word by word with field label
3 : searchable only selectively
(F): field is searchable only via basic index

Command Field Name Examples Notes
(F) S AB Abstract F antidepressants/AB Each document contains an abridged abstract in English
D F AI Abstract Indicator F...AND AI=?
D AI=?
F AI=abstract online
Selects documents with an abstract online.
D F S AU Author F AU=Centre for Reviews? Centre for Reviews and Dissemination only available for Author.
D F S CT Controlled Terms F CT=ibuprofen
D CT=ibupro?
 
    F CT D dementia Indented descriptors are included.
    D CT T dementia Requesting tree structure.
    D CT=dementia;ALL Requesting additional information.
  /QF=... Qualifier F CT=breast neoplasms/QF=pathology Searches Controlled Terms in combination with a qualifier.
    D QF=a? List of all qualifiers (see appendix).
D F S DOI Digital Object Identifier D DOI=?
F DOI="10.1002/14651858"
Must be set in quotation marks.
A DOI is a unique and persistent identification code for digital objects.
D F S DT Document Type F DT=abstracts of quality assessed systematic reviews
D DT=?
 
S ISS Issue Iss: 2006 Issue 3 Part of SO.
D 1 F 1 S JT Journal Title F JT=?abstracts? Part of SO.
All documents are taken form "Database of Abstracts of Reviews of Effectiveness".
D F S LA Language F... AND LA=engl
D LA=?
Only English documents are available.
D F S ND Number of Document F ND=CDAR12007003863  
S PAGE Pages PAGE:  DA20000170 Contains an abbreviated version of the ND as the pages are not numbered. Part of SO. 
S PD Publication Date
 
Part of SO.
D F S PY Publication Year F... AND PY>=2002 Part of PD.
D F S RA Reference Author F RA=pagliaro l Part of RF.
D 1 F 1 S RF References F RF=?health? Literature reference. Made up of: RA, RTI, RJ, RY and other bibliographical details.
D F S RJ Referenced Journal F RJ=diabetes care Part of RF.
D F S RN Number of References F RN=0001 Is always =1.
D 1 F 1 S RTI Reference Title F RTI=?placebo? Part of RF.
D F S RY Referenced Year F RY=2002 Part of RF.
S SO Source SO:  Database of Abstracts of Reviews of Effectiveness (Issue 2003/1); p. DA20012645 /2001/ Made up of JT(full title), ISS, PAGE and PD.
D F S STA Status F STA=new
D STA=?
 
(F) S TI Title F asthma/TI  
Output of Search Results

By means of the commands: SHOW (S) / MAIL / SDI.

Corresponding to the copyright rules use the parame-ter USE=DLOAD if necessary.

You may ask for all data fields, single data fields, or sets of data fields. If the output fields are not specified explicitly, the standard field set (F=STD) is used in all output commands.

Fields set at output:

Command Field Set Associated Datafields
F=STD Standard same as F=ALL without RF, RJ
F=ALL All data fields ND, AU, CA, TI, SO (incl. JT, ISS, PAGE, PD), LA, DT, RN, CT, AB, RF (incl. RA, RTI, RJ, RY), RJ
F=BIB Bibliographic fields ND,AU, CA, TI, SO, LA, DT, RN
F=DES Descriptors CT
F=REFS References RF (incl. RA, RTI, RJ, RY), RJ
Sample Search(es)

Subject: Adverse effects of Ibuprofen.

1. Search via DIMDI SmartSearch

Screenshot: CDAR94 Sample Search

2. Search via DIMDI ClassicSearch

Profile table:

Parameter Counter Number of Hits Query
C= 1 13521   CDAR94
S= 2 23   CT=IBUPROFEN/AE

 

Sample Record(s)

2/1 of 23    DIMDI: Database of Abstracts of Reviews of Effects (CDAR94) © 2010 University of York. Published by John Wiley & Sons, Ltd.

ND: CDAR12010000266
AU: Centre for Reviews and Dissemination
TI: Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever (Structured abstract)
SO: Database of Abstracts of Reviews of Effectiveness (2010 Issue 4); p. DA12010000266 /2009/
LA: English
DT: Abstracts of quality assessed systematic reviews
RN: 0001
CT: Acetaminophen/adverse effects; Acetaminophen/therapeutic use; Algorithms; Analgesics, Non-Narcotic/adverse effects; Analgesics, Non-Narcotic/therapeutic use; Anaphylaxis/epidemiology; Anaphylaxis/etiology; Fever/complications; Fever/drug therapy; Gastrointestinal Hemorrhage/epidemiology; Gastrointestinal Hemorrhage/etiology; Hospitalization/statistics & numerical data; Ibuprofen/adverse effects; Ibuprofen/therapeutic use; Liver Diseases/epidemiology; Liver Diseases/etiology; Pain/complications; Pain/drug therapy
AB: CRD summary
This review concluded that ibuprofen, paracetamol and placebo for paediatric pain and fever had comparable profiles for gastrointestinal symptoms, asthma and renal adverse effects. This was generally a well-conducted review and the authors' conclusions are likely to be reliable, although (as the authors acknowledged) some caution may be merited based on comparisons with placebo from a few small studies.
Authors' objectives
To compare the tolerability and safety of ibuprofen and paracetamol when used as anti-pyretic and analgesic agents in children up to 18 years of age.
Searching
MEDLINE, EMBASE, The Cochrane Library, ACP Journal Club and Pascal were searched for publications in English, French, Dutch, German or Portuguese. Search dates ranged from 1950 to November 2008. The search strategy for one database was available as an online supplement; other databases were available on request from the authors.
Study selection
Randomised controlled trials (RCTs), controlled observational studies (assessing rare adverse events) and large case series (>1,000 participants) that compared efficacy, safety and tolerability of ibuprofen and/or paracetamol with placebo in children up to 18 years of age with pain and/or fever were eligible for inclusion. Outcome measures included: adverse events that required discontinuation of medication; systemic reactions related to ibuprofen or paracetamol; fatal or life-threatening adverse events or those that required hospitalisation; and serious adverse events that did not require hospitalisation.
Included studies were undertaken in North America, Europe and Asia (half of them in either USA or France). Most of the included RCTs compared ibuprofen with paracetamol. A third of the studies were funded by pharmaceutical companies.
Two reviewers independently selected studies for inclusion in the review. Disagreements were resolved through consensus and checked by a third reviewer.
Validity assessment
Two reviewers independently assessed study validity using checklists for RCTs and other study designs from CRD report 4. No specific details of criteria used were reported but use of allocation concealment, sequence generation, blinding and intention to treat analysis were reported. Disagreements were resolved through consensus.
Data extraction
Data for dichotomous outcomes were extracted to calculate relative risks (RR) or odds ratios (OR) with 95% confidence intervals (CIs). Means and standard deviations were extracted for continuous outcomes to calculate the weighted mean difference (WMD) and 95% CI.
...
RF: Southey ER; Soares-Weiser K; Kleijnen J; Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever; Current Medical Research and Opinion; 25(9); 2207-2222; 2009REFS.RJ:Current Medical Research and Opinion

   Illustration (book): Online full-text available  full text

*** End of SHOW ***

The sample record is reduced in its length.

Output format: SHOW F=ALL

Contact

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Appendix

Appendix

List of Qualifiers

Abnormalities
Administration & Dosage
Adverse Effects
Agonists
Analogs & Derivatives
Analysis
Anatomy & Histology
Antagonists & Inhibitors
Biosynthesis
Blood
Blood Supply
Cerebrospinal Fluid
Chemical Synthesis
Chemically Induced
Chemistry
Classification
Clinical Trial
Complication
Complications
Congenital
Contraindications
Cytology
Deficiency
Diagnosis
Diagnostic Use
Diet Therapy
Drug Effects
Drug Therapy
Economics
Education
Embryology
Enzymology
Epidemilogy
Ethics
Ethnology
Etiology
Genetics
Growth & Development
History
Immunology
Injuries
Innervation
Instrumentation
Isolation & Purification
Legislation & Jurisprudence
Manpower
Metabolism
Mehods
Microbiology
Mortality
Nursing
Organisation & Administration
Parasitology
Pathogenicity
Pathology
Pharmacokinetics
Pharmacology
Physiology
Physiopathology
Poisoning
Prevention
Prevention & Control
Psychology
Radiation Effects
Radiography
Radionuclide Imaging
Radiotherapy
Rehabilitation
Secondary
Secretion
Standards
Statistics & Numerical Data
Supply & Distribution
Surgery
Therapeutic Use
Therapy
Toxicity
Transmission
Transplantation
Trends
Ultrasonography
Ultrastructure
Urine
Utilization
Veterinary
Virology

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