Cochrane Central Register of Controlled Trials
Accesskeys
- [Alt + 0] - Homepage
- [Alt + 1] - to the top
- [Alt + 5] - Search Form
- [Alt + 6] - Sitemap
- [Alt + 7] - to within-page navigation
- [Alt + 8] - to content
- [Alt + 9] - Contact Form
Global Servicelinks
Navigation
content
Detailed Information: Cochrane Central Register of Controlled Trials
(CCTR93)
Clinical Trials
The Cochrane Central Register of Controlled Trials (Central; Clinical Trials) is a bibliography of controlled trials identified by contributers of the Cochrane Collaboration and others, as a part of an international effort to hand search the world´s journals and create an unbiased source of data for systematic reviews. Central includes reports published in conference proceedings and in many other sources not currently listed in MEDLINE or other bibliographic databases.
Content navigation
- Database Content: Subject Coverage | Type | Language | Sources | Superbases
- Database Resources: File Size | File Data | Update Cycle
- Query: Special Notes | Vocabulary | Searchable Data Fields | Data Fields, alphabetical | Output of Search Results | Sample Search(es) | Sample Record(s)
- Contact: Producer | Contact Person
- Appendix: Appendix
Database Content
| Subject Coverage | Medicine and Related Fields |
|---|---|
| Type | Literature database |
| Language | English |
| Sources | Scientific Journals, Conference proceedings, and the like |
| Superbases | There are predefined databases groups (superbase) for several subjects. The database Cochrane Central Register of Controlled Trials is part of the following superbases: |
Database Resources
| File Size | 671,683 (Status 06/2012) |
|---|---|
| File Data |
You will find the number of database records in the current update status. |
| Update Cycle | Monthly |
Query
Special Notes
With every update the whole file is reloaded. Therefore standing orders (SDI) are not possible.
Vocabulary
Controlled Terms (CT): MeSH thesaurus with polyhierarchical
structure
Language of vocabulary: English
The hierarchical structure of the thesaurus allows a one step search for indented descriptors using the command FIND CT DOWN … (explosion). CT can be limited using more than 80 qualifiers, e.g. epidemiology of a disease (FIND CT=.../QF=ep). List of qualifiers see appendix.
Descriptors, describing the major topics of an article are weighted and marked in the document by an asterisk (HIV SEROPOSITIVITY/*). You can search for weighted descriptors with the command FIND CT=.../W=1.
The command DISPLAY CT TREE ... displays the structure of the thesaurus.
DISPLAY CT= ... ;ALL displays all available additional information to a descriptor (see table below).
The following additional information for controlled terms (CT) is available:
| Code | Field Name | Description |
|---|---|---|
| ANN | Annotations | Indexing annotations |
| AQ | Allowed Qualifier | Qualifiers allowed for limiting the controlled terms |
| CC | Classification Code | One descriptor may have several classification codes corresponding to the different branches in the polyhierarchic thesaurus |
| CR | CAS- Registry- Number | |
| DA | Date | Date, the record was added to the system |
| ECOM | Entry Combination | Information on use of combinations for related concepts |
| HIS | History-Notes | Information on entry date of the descriptor and formerly used controlled terms |
| MAE | Major Established | Introduction date as major descriptor |
| N1 | Preferred Name | Preferred name of chemicals/td> |
| PACT | Pharmacological Action | Pharmacological action descriptor |
| PI | Previous Indexing | Previous Indexing |
| PMN | Public MeSH Note | Information on entry date of the descriptor and formaerly used controlled terms |
| SCN | Scope Notes | definitions |
| SYN | Synonym | Information on entry terms |
| USE | Use | Print Version |
Searchable Data Fields
The following document sections are considered with the free text search (FT):
Abstract (AB)
Controlled Term (CT)
Document Type (DT)
Original Title (OTI)
Title (TI)
Search language(s) in the Basic Index: English
Data Fields, alphabetical
Explanation:
D = DISPLAY F = FIND S = SHOW
1 : front-end-masking recommended
2 : searchable word by word with field label
3 : searchable only selectively
(F): field is searchable only via basic index
| Command | Field Name | Examples | Notes |
|---|---|---|---|
| (F) S | AB Abstract | F karelia/AB | Approx. 72 % of the documents contain abstracts. |
| D F S | AU Author | F AU=geraci e | |
| D 2 F 2 S | CS Corporate Source | F CS=health | |
| D 1 F 1 S | CT Controlled Terms | F CT=ibuprofen? | Approx. 95 % of documents contain controlled terms. Very different field contents because of different sources, e.g. numbers as well. We recommend masking. |
| /QF=... Qualifier | F CT=breast neoplasms/QF=pathology | Searches Controlled Terms in combination with a qualifier. | |
| D QF=? | List of all qualifiers (see appendix). | ||
| /W=1 Weighting | F CT=hiv seropositivity/W=1 | Search for weighted Controlled Terms. Priorities were seldom established. Not useful for the search. |
|
| D 1 F 1 S | CT Controlled Terms | F CT=ibuprofen? | Approx. 95 % of documents contain controlled terms. Very different field contents because of different sources, e.g. numbers as well. We recommend masking. |
| F CT D dementia | Indented descriptors are included. | ||
| D CT T dementia | Requesting tree structure. | ||
| D CT=dementia;ALL | Requesting additional information. | ||
| /QF=... Qualifier | F CT= breast neoplasms/QF= pathology | Searches Controlled Terms in combination with a qualifier. | |
| D QF=a | Liste aller QF (siehe Anhang). | ||
| /W=1 Weighting | F CT=hiv seropositivity/W=1 | Weighting of controlled terms. | |
| D F 1 S | DT Document Type | F DT=guideline D DT=? |
Very different field contents because of different sources, e.g. numbers as well. We recommend masking. |
| D F S | EDR Editor | F EDR= kassell nf | |
| S | ISS Issue | Iss: Issue 2003/1 | Part of SO. |
| D 1 F 1 S | JT Journal Title | F JT=?abstracts? | Contains also conferences and symposiums. Part of SO. |
| D F S | LA Language | F... AND LA=engl D LA= ? |
|
| D F S | ND Number of Document | F ND= CN-00000777 | |
| S | NOTE Notes | Note: MEDLINE - 91338646 | |
| (F) S | OTI Original Title | F lunge/oti | Part of TI. |
| S | PAGE Pages | PAGE: 407-11 | Part of SO. |
| D F S | PD Publication Date | F PD=2003 | Part of SO. |
| D 2 F 2 S | PU Publisher | F PU= springer | |
| D F S | PY Publication Year | F... AND PY>=2002 | Part of PD. |
| S | SO Source | SO: Lancet; VOL: 2 (7458); p. 291-5 /1966 Aug 6/ | Consisting of JT (long title), VOL, ISS, PAGE and PD. |
| (F) S | TI Title | F asthma/TI | |
| S | VOL Volume | VOL: 23 | Part of SO. |
Output of Search Results
By means of the -commands: SHOW (S) / MAIL / SDI.
Corresponding to the copyright rules use the parameter USE=DLOAD if necessary.
You may ask for all data fields, single data fields, or sets of data fields. If the output fields are not specified explicitly, the standard field set (F=STD) is used in all output commands.
Fields set at output:
| Command | Field Set | Associated Datafields |
|---|---|---|
| F=STD | Standard | Same as F=ALL |
| F=ALL | All data fields | ND, AU, TI, SO (incl. JT, ISS, PAGE, PD), LA, CS, DT, CT, NOTE, AB |
| F=BIB | Bibliographic fields | ND, AU, TI, SO, LA, CS, DT |
| F=DES | Descriptors | CT |
Sample Search(es)
Subject: Asthma due to allergies
1. Search via DIMDI SmartSearch
2. Search via DIMDI ClassicSearch
Profile table:
| Parameter | Counter | Number of Hits | Query |
|---|---|---|---|
| C= | 1 | 635167 | CCTR93 |
| S= | 2 | 10445 | ASTHMA/TI |
| S= | 3 | 13605 | CT D ASTHMA |
| 4 | 5929 | (ALLERG? OR HYPERSENSITIV?)/TI | |
| 5 | 1285 | (2 OR 3) AND 4 |
Sample Record(s)
DIMDI: Cochrane Central Register of Controlled Trials (CCTR93) © The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
| ND: | CN-00749078 |
| AU: | Pedroletti C; Millinger E; Dahlén B; Söderman P; Zetterström O |
| TI: | Clinical effects of purified air administered to the breathing zone in allergic asthma: A double-blind randomized cross-over trial. |
| SO: | Respiratory medicine; VOL: 103 (9); p. 1313-9 /2009 Sep/ |
| LA: | English |
| CS: | Department of Women and Child Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. christophe.pedroletti@karolinska.se |
| DT: | REFERENCE-NEW; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| CT: | Adult; Child; Female; Humans; Male; Young Adult; Administration, Inhalation; Adolescent; Air/*; Asthma/physiopathology; Asthma/*therapy; Cross-Over Studies; Double-Blind Method; Exhalation; Nitric Oxide/analysis; Nitric Oxide/*metabolism; Quality of Life/*; Sleep; Spirometry; Treatment Outcome |
| NOTE: | PUBMED - 19443189 EMBASE - 2009403621 |
| AB: | BACKGROUND: Exposure to inhaled allergens is a pathogenetic factor in allergic asthma. However, most studies that previously looked at air cleaning devices have shown little or no effect on patients with perennial allergic asthma. AIMS AND OBJECTIVES: We examined a novel treatment using temperature regulated laminar airflow with a very low particle concentration directed to the breathing zone of teenagers and young adults with mild to moderate allergic asthma during night sleep. We hypothesised that the decreased allergen exposure during the night would have an effect on bronchial inflammation and quality of life. METHOD: Twenty-two patients (mean 18.8 years) were randomized to start with active or placebo treatment for 10 weeks. All patients received both active and placebo treatment with unfiltered air, with a 2-week wash-out period in between treatments. Maintenance treatment with inhaled corticosteroids was unaltered during the trial period. Health related quality of life (miniAQLQ) was the primary effectiveness measure. Exhaled nitric oxide (FeNO) and spirometry were also investigated. RESULTS: Active treatment resulted in an improved miniAQLQ compared to placebo (mean score 0.54, p<0.05, n=20). An effect on bronchial inflammation was also detected with significantly lower FeNO values during the active treatment period (mean -6.95 ppb, p<0.05, n=22). Both effects were evident after 5 weeks. The change in lung function was not statistically significant. CONCLUSION: Clean air, administered directly to the breathing zone during sleep, can have a positive effect on bronchial inflammation and quality of life in patients with perennial allergic asthma. |
full
text
*** End of SHOW ***
Output format: SHOW F=ALL
Contact
Producer
- Cochrane Collaboration
Summertown Pavilion
18-24 Middle Way
Oxford OX2 7LG
Great Britain
Phone: +44 1865 310138
Fax: +44 1865 316023
Contact Person
- Database Search:
DIMDI
Phone: +49 221 4724-315
E-mail: Helpdesk Databases - Service, Contract, Prices:
DIMDI
Phone: +49 221 4724-270
E-mail: Technical Helpdesk
Appendix
Appendix
List of Qualifiers
Abnormalities
Administration & Dosage
Adverse Effects
Agonists
Analogs & Derivatives
Analysis
Anatomy & Histology
Antagonists & Inhibitors
Biosynthesis
Blood
Blood Supply
Cerebrospinal Fluid
Chemical Synthesis
Chemically Induced
Chemistry
Classification
Clinical Trial
Complication
Complications
Congenital
Contraindications
Cytology
Deficiency
Diagnosis
Diagnostic Use
Diet Therapy
Drug Effects
Drug Therapy
Economics
Education
Embryology
Enzymology
Epidemilogy
Ethics
Ethnology
Etiology
Genetics
Growth & Development
History
Immunology
Injuries
Innervation
Instrumentation
Isolation & Purification
Legislation & Jurisprudence
Manpower
Metabolism
Methods
Microbiology
Mortality
Nursing
Organisation & Administration
Parasitology
Pathogenicity
Pathology
Pharmacokinetics
Pharmacology
Physiology
Physiopathology
Poisoning
Prevention
Prevention & Control
Psychology
Radiation Effects
Radiography
Radionuclide Imaging
Radiotherapy
Rehabilitation
Secondary
Secretion
Standards
Statistics & Numerical Data
Supply & Distribution
Surgery
Therapeutic Use
Therapy
Toxicity
Transmission
Transplantation
Trends
Ultrasonography
Ultrastructure
Urine
Utilization
Veterinary
Virology
- Copyright: DIMDI -