Cochrane Database of Systematic Reviews

In die Datenbank CDSR wurde die Cochrane Datenbank für methodische Übersichtsarbeiten (Cochrane Database of Methodology Reviews, CDMR) integriert. CDMR ist ein Register von Studien zur Methodik der Erstellung systematischer Übersichtsarbeiten. Über die Dokumentnummer (ND) können Sie Dokumente aus der CDMR gezielt aufrufen (FIND ND=MR?). Siehe auch Suchbeispiele.

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Controlled Terms (CT): MeSH-Thesaurus mit polyhierarchischer Struktur
Das Feld CT ist nur im Dokumenttyp Review enthalten.
Sprache des Vokabulars: Englisch

Die hierarchische Struktur des Thesaurus ermöglicht Recherchen in einem Schritt nach inhaltlich zusammengehörenden Deskriptoren durch eine FIND CT DOWN...-Suche. Zudem können die CT durch Verwendung von Qualifier (über 80) weiter eingeschränkt werden, z. B.: Epidemiologie einer Krankheit (F CT=.../QF=ep).

Deskriptoren (CT), die Hauptaspekte eines Dokumentes beschreiben, sind gewichtet und durch einem Stern gekennzeichnet (HIV SEROPOSITIVITY/*). Mit FIND CT=.../W=1 kann nach gewichteten Deskriptoren gesucht werden.

Mit DISPLAY CT TREE ... kann die Struktur des Thesaurus dargestellt werden.

Mit DISPLAY CT=...; ALL werden Zusatzinformationen zu den Deskriptoren aufgerufen.

Folgende Zusatzinformationen zu den Controlled Terms sind verfügbar:

Thema: Arzneimitteltherapie bei Schizophrenie 

1. Suche über DIMDI SmartSearch

Bei dieser Suchmöglichkeit kann der Qualifier "drug therapy" nicht mitgesucht werden.

2. Suche über  DIMDI ClassicSearch

Thema:
Anzeige von Suchstrategien in Dokumenten aus der integrierten Datenbank "Cochrane Database of Methodology Reviews (CDMR)" mit Hilfe der Dokumentnummer. Durch Angabe der Dokumentnummer ND=MR? werden nur Dokumente aus der CDMR angezeigt.

Suchprofil

DIMDI: Cochrane Database of Systematic Reviews (CDSR93) © The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

ND:	CD007811
AU:	Omori Ichiro M; Wang Jijun
CA:	Toyokawa City Hospital, Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Department of EEG Source Imaging, Koumei 1-19, Toyokawa, Aichi, Japan, 442-8561, Shanghai, Shanghai, China, 200030, JP
CNA:	HM-SCHIZ ... Cochrane Schizophrenia Group
TI:	Sulpiride versus placebo for schizophrenia
SO:	Cochrane Database of Systematic Reviews (2010 Issue 11); p. CD007811 /2009 2. Issue/
LA:	English
DT:	Review, Edited (no change to conclusions)
ISSOD:	10112010
RN:	0061
CT:	Humans; Antipsychotic Agents/*therapeutic use; Placebos/therapeutic use; Randomized Controlled Trials as Topic; Schizophrenia/* drug therapy; Sulpiride/*therapeutic use
STA:	Edited (no change to conclusions)
PLS:	Plain language summary Sulpiride versus placebo for schizophrenia Schizophrenia is a severe mental illness characterised by a mixture of symptoms such as hallucinations, delusions, disorganisation and social withdrawal. For some it can be a life-long condition and people with this diagnosis are usually treated with antipsychotic drugs. There can be quite a large difference in cost between recently developed antipsychotics (second generation) and the older ones (first generation), but the older drugs can have considerably more movement side effects and many people find them difficult to tolerate. In developing countries cost of medication can be a major factor in prescribing, so the first generation drugs are used the most. ...
AB:	Background Sulpiride is a relatively old antipsychotic drug reputed to have low incidence of adverse effects and an effect on the negative symptoms of schizophrenia. This relatively inexpensive antipsychotic drug has a similar neuropharmacological profile to several novel atypical drugs. Objectives To evaluate the effects of sulpiride for schizophrenia and other similar serious mental illnesses in comparison with placebo. Search strategy We searched the Cochrane Schizophrenia Group Trials Register (September 2008) and references of all identified studies for further trial citations. We contacted pharmaceutical companies and authors of trials for additional information. Selection criteria We included all randomised controlled trials (RCTs) comparing sulpiride with placebo for people with schizophrenia and other types of schizophrenia-like psychoses. The primary outcome of interest was clinically significant response in global state. ...
References to studies included in this review Blanco 1972 {published data only}
RF:	Mezquita Blanco J; Cubillo Sanchez J; Aizpiri Diaz J; Zubia Zubia B; Clinical trial with sulpiride and placebo in chronic schizophrenics study of 89 patients using the Harris-Letemendia-Willems scale; Ensayo clinico con Sulpiride y placebo en esquizofrenicos cronicos. Estudio de 89 enfermos, con aplicacion de la escala de Harris, Letemendia y Willems; 35; 453-72; 1972  RJ: Archivos de Neurobiologia - Madrid
...
References to studies excluded from this review Benoit 1969 {published data only}
RF:	Benoit JC; Delagrange G; Richou A; Souchon G; Sow I; Sivadon P; Contribution to the clinical study of a new neuroleptic: sulpiride; Contribution a l'etude clinique d'un nouveau neuroleptique: le sulpiride; 45(15); 958-63; 1969  RJ: Semaine des Hopitaux
...
Gong 2001 {published data only}
RF:	Gong BQ; Mu JM; Song HL; Song LX; Li DJ; A comparison study of using clozapine in combination with sulpiride and simple using clozapine or sulpiride in treatment schizophrenia; 2(6); 20-3; 2001  RJ: Journal of Chinease Clinical Medicine
...
Kotler 2004 {published data only}
RF:	Kotler M; Strous RD; Reznik I; Shwartz S; Weizman A; Spivak B; Sulpiride augmentation of olanzapine in the management of treatment-resistant chronic schizophrenia: evidence for improvement of mood symptomatology; 19(1); 23-6; 2004; 15101566  RJ: International Clinical Psychopharmacology
...
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